Gaidin wrote:

One of our computers here at work has and unknown issue. AV is up to
date, no adware/spyware to be found. Any link that is clicked on
inside an email brings up the users default home page instead of what
the link points to. Everything worked fine yesterday, this just began
this morning.

Is it a "Locate Link Browser" window? See this:
http://support.microsoft.com/?kbid=821692