We run Outlook 2007. A user opened Outlook and received the message "Cannot
start Microsoft Office Outlook. Cannot open the Outlook window." After much
research, the only option that worked was creating a new profile. The old
profile name was "Outlook". I created a new profile using the username.
Outlook opens fine, however, the user lost all their cached entries (.nk2).
I copied the "Outlook.nk2" file
(C:\Users\username\AppData\Roaming\Microsoft\Outlo ok) and renamed it to the
username, which is the same name as their profile. It still doesn't work.
Everytime the user opens Outlook, the username.nk2 is overwritten with a
blank username.nk2 file. Am I missing something?

teenzbutler;112734 Wrote:
We run Outlook 2007. A user opened Outlook and received the message
"Cannot start Microsoft Office Outlook. Cannot open the Outlook
window."

If the old mail profile still exists, configure Outlook to ask for the
mail profile when starting and run Outlook once with the /resetnavpane
command switch. That should cure this problem and your problem with the
copied NK2 file as well. Delete the new mail profile because you won't
need it.


--
Brian Tillman

[MVP-Outlook]
http://forums.slipstick.com